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Effects of Immunall
on activity of cells of the immune system in poultry, pigs and cattle; In vitro
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Immunall-fraction doubles the activity of macrophages in vitro |
T-lymphocytes, poultry
(peripheral blood)![]() |
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T-lymphocytes, piglet
(peripheral blood)![]() |
Herbal fraction
in Immunall stimulates the proliferative respons of peripheral T-cells of
piglets to Con A with a factor 2.5. Remark: piglet shortly before
weaning |
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Immunall tincture stimulates the proliferative respons of peripheral T-cells to Con A with a factor 9.1. |
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T-lymphocytes, calf
(peripheral blood)![]() |
Immunall tincture doubles the proliferative respons of peripheral T-cells to Con A. |
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| Extended in vitro research in poultry (may 2001, Agricultural University) | |
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Immunall doubles
the activity of macrophages with or without the presence of antigen (LPS).
Optimal stimulation
at high concentration of Immunall. |
| Activity of macrophages: NaNO2 production after incubation of 48 hours at 41º C recorded by measurement of extinction in ELISA-reader. | |
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Immunall almost
doubles the proliferative response of T-cells to Con A.
Optimal stimulation at low
concentration of Bioltan. |
| Hypothesis: Immunall stimulates macrophages and specific T-cells. T-cells show a high stimulation index in the presence of low doses Immunall. In that range macrophages show a minor activity, but produce probably enough stimulating factors to support the immune response of antigen-triggered T-cells. In the presence of high doses Immunall macrophages are highly stimulated, producing a lot of nitrogendioxide which is toxic for T-cells. The proliferation of T-cells will be inhibited. | |